There are just so many variables that can affect the handling and getting the balance right is a real art and only hours and hours of testing would really give some good answers. Even then quite different set ups might actually achieve a similar end result in terms of performance/lap time.
Ride height front/rear, suspension and arb settings, tyres inc. different pressures, front/rear track width, overall stiffness of car [ie bushes,cage,strut braces, seam welding] etc. all affect handling overall and can affect each other as well which is why finding what really is the best set up is an absolute art and in reality you probably never really get there due to the variables of different conditions thrown in
The best anyone can really aim for is a good base line set up and then tweak from there as required, only if of course it's that important such as if actually competing. Otherwise for road and track days etc. a good base setting should be adequate.
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