Hi Adam, welcome to SCN.
Yes Quaife do a diff for the VW 02Q 6 speed box fitted to the Cupra, as do Peloquin and Wavetrac. They will cost in the region of £700 not including fitting. Some of the folks on here are already discussing this for their Leon's here -
http://www.seatcupra.net/forums/showthread.php?t=246432&highlight=diff
A good suspension kit, anti roll bar upgrades and WALK anti-lift kit and engine mounts will also go some way to aid handling and
help with traction, but the diff would be the cherry on top. Worth noting that if you had a diff fitted its a good time to get the clutch uprated at the same time so you maybe budgeting for anything upwards of £1600.
If you 'don't' include the cost of the remap which are usually around £400, a spend of £1000-£1500 on top of the remap then your aiming towards stage2+ area which is going to deliver around 340-360hp at the clutch. Dependent on the map or how aggressive you are with the setup as (REVO is adjustable).
No one has detonated an engine yet that I personally know of with many of these cars running in excess of 300hp at least and the same engine being run in the Golf Edition 30 and Audi S3 they have a great number being modified and its rare I've heard of common failures. A turbo went on one recently, but its believed it sucked something in it shouldn't of which ended up ruining the blades, a replacement turbo was fitted and as far as I know all is now well.
The basic mods required for a strong stage2+ would be:
An up-rated fuel pump (either APR pump which is a complete replacement unit for around £650 or an upgrade kit which replaces the internals of the OEM pump usually around £300),
a Full Milltek or alternatively a Blueflame Exhaust (inc downpipe) £800 - £1000,
a full intake is proven to give a good increase as much as 15-20hp the intake of the moment is the ITG kit which is around £350, but you also have DBilas, Backdraft, and Forge will start shipping their Twintake system soon too.
then you can also add an up-rated intercooler (best examples being either APR or Forge Twintercooler which range from £500-£900 fitted or a cheaper alternative would be an Audi S3 OEM intercooler which come in around £350 fitted)
Once you have those mods your most of the way set for going to a bigger turbo in the future if you wanted to as well.